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Funded PhD position; at Sager Laboratory of Cardiovascular Inflammation; Technical University of Munich; in Germany

The German Heart Center of the Free State of Bavaria associated to the Technical University of Munich is a clinic with international reputation and a state of the art technical and medical equipment.

The Sager Laboratory of cardiovascular inflammation at the Department of Cardiovascular Diseases is seeking a
PhD student (m/f)

The “European Research Council starting grant” research group of Dr. Hendrik Sager is looking to recruit a highly-motivated PhD student (m/f) to join a dynamic international research team at the German Heart Center Munich, department of cardiology. Our research focusses on the role of the immune system in cardiovascular disease. Specifically, we are interested in the origin, function and fate of innate immune cells (monocytes, macrophages, neutrophils) in atherosclerosis and wound healing after myocardial infarction. Based on new mechanistic understanding, we seek to develop novel therapeutic concepts. We are part of the German Heart Center Munich and aim translate our findings to better understand and improve human health. We are funded by the “European Research Council ( ERC Starting Grant 2017 awarded to H. Sager)”, “Deutsche Forschungsgemeinschaft”, “Deutsches Zentrum für Herz-Kreislauf-Forschung”, “Else-Kröner-Fresenius-Stiftung” and “Deutsche Herzstiftung”.

The successful applicant (m/f) should have an excellent command of flow cytometry techniques, in addition to standard molecular biology.

Your application should include:

  • Cover letter describing your research interest and why you are suitable for the position (maximum 1 page)CV including a list of relevant publications

    Copy of the official academic transcript of your degree or a letter stating when your degree will be obtained

    Names, e-mail addresses, and telephone numbers for academic references/recommendation letters

Recent publications:
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Sager HB , Hulsmans M, Lavine KJ, Beltrami Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circ Res. 2016 Sep 16;119(7): 853-64. doi: 10.1161/ CIRCRESAHA .116.309001. (IF=11.6)

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.
Sager HB , Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M.

Sci Transl Med. 2016 Jun 8;8(342): 342ra80. doi: 10.1126/scitranslmed.aaf1435. (IF=16.3)

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Sager HB , Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circulation. 2015 Nov 17;132(20): 1880-90. doi: 10.1161/ CIRCULATIONAHA .115.016160. (IF=17)

Myocardial Infarction Activates CCR2 Hematopoietic Stem and Progenitor Cells.

Dutta P*, Sager HB * (contributed equally), Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M.

Cell Stem Cell. 2015 May 7;16(5): 477-87. doi: 10.1016/j.stem.2015.04.008. (IF=22.4)

Chronic variable stress activates hematopoietic stem cells.

Heidt T*, Sager HB * (contributed equally), Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M.

Nat Med. 2014 Jul;20(7): 754-8. doi: 10.1038/nm.3589. (IF=27.4)

Our offer:
The position covers a three-year period with possibility of extension, starting January 2018. The salary is based on the TV-L (70% German TV-L E13).

The German Heart Center Munich promotes professional equality between women and men and provides the same employment opportunity for severely disabled people in case of equal qualifications.

Hendrik Sager, MD, Principal Investigator, telephone +49 89 1218 2935

Thomas Schmid, Head of Recruiting / HR, telephone +49 89 1218 1734

Please be directed to our webpage for more information:

Please send us your application until October 31th, 2017 by E-Mail to: .

Interview expenses will not be reimbursed.

Deutsches Herzzentrum München, Personalverwaltung, Lazarettstraße 36, 80636 München, …

Deadline: October 31, 2017.

Apply Now