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Clinical Research Fellowship PhD Studentship at Imperial College London, UK, , Deadline: August 05, 2019

The Experimental Medicine Initiative to Explore New Therapies (EMINENT) invite applications for a prestigious fully-funded, BRC-MRC-GSK Clinical Research Fellowship-PhD studentship at the Imperial College London. EMINENT is an MRC-Industry co-funded programme, which brings together investigators and researchers from University College London (UCL), the University of Cambridge, the University of Glasgow, the University of Newcastle,…

Job listing information

  • Reference MED01314
  • Date posted 4 July 2019
  • Closing date 5 August 2019

Job description

Job summary

The Experimental Medicine Initiative to Explore New Therapies (EMINENT) invite applications for a prestigious fully-funded, BRC-MRC-GSK Clinical Research Fellowship-PhD studentship at the Imperial College London.EMINENT is an MRC-Industry co-funded programme, which brings together investigators and researchers from University College London (UCL), the University of Cambridge, the University of Glasgow, the University of Newcastle, Imperial College London and GlaxoSmithKline (GSK) to undertake novel science that would not be possible outside such a cross-sector network. Academic researchers gain unprecedented access to GSK’s unlicensed asset portfolio, via collaborative preclinical and experimental medicine studies aimed at enhancing the understanding of disease mechanisms and accelerating the development of novel therapeutics for patients in underserved disease areas.The overarching aim of EMINENT is to deliver significant scientific progress, to understand disease mechanisms, and develop new therapeutic strategies. Impact and success will be assessed across three key areas: Scientific innovation, network cohesion, and building research capacity through creating a cadre of scientific and clinical leaders promoting the benefits of multiple partner clinical/ preclinical studies holding a rich base of knowledge and skills developed within the unique industrial-academic research environment of EMINENT.The StudentshipThis innovative studentship is a partnership between the NIHR Biomedical Research Centre at Imperial College, the Medical Research Council (MRC) and GSK, and provides an unrivalled opportunity to undertake high quality research in experimental medicine in collaboration with academic and industrial supervisors. The studentship should particularly appeal to clinicians with a subspecialty interest and experience in respiratory medicine, infectious disease/virology and immunology. The studentship is available from autumn 2019 and the award covers the Fellow’s salary for three years, research consumables and PhD fees.The ProjectsThe project will represent a unique opportunity to join the collaboration between Prof Openshaw, colleagues across the EMINENT network, and GSK. The successful candidate will join Imperial College London with the aim of completing their doctoral studies.

Duties and responsibilities

The successful applicant will join an experienced team to become skilled in leading the clinical conduct and analysis of human RSV infection challenge studies in older adults, to investigate age-related factors responsible for increased susceptibility to more severe disease in this age group. This will include histological and transcriptomic analysis of lower airway tissue responses to infection to determine the role of dysregulated inflammation with the aim of identifying potential targets or pathways for intervention to improve disease outcome.  The project will provide the successful applicants with the opportunity to apply their strengths to pre-clinical and experimental medicine and gain unique hands-on experience in translational medicine.The successful applicant will have the opportunity to spend time embedded within GSK as well as working with academic collaborators. During the industrial placement, applicants will pursue their project work in collaboration with the relevant GSK project teams and gain an understanding of how science influences R&D decision making. The structured mentoring and training programme afforded by EMINENT will allow candidates to develop as academic clinicians enhanced with industry experience in designing and conducting experimental medicine studies. 

Essential requirements

It is essential that the applicant is fully registered with the GMC, and desirable that they already hold a National Training Number.

Further information

As this post is exempt from the Rehabilitation of Offenders Act 1974, a satisfactory enhanced for regulated activity Disclosure and Barring Service check will be required for the successful candidate. Further information about the DBS disclosure process can be found at http://www.homeoffice.gov.uk/agencies-public-bodies/dbs/ or by telephoning 0870 90 90 811. You may also wish to view the College’s policy statements on the Recruitment and Employment of Ex-Offenders and the Secure Storage, Use, Retention & Disposal of Disclosures and Disclosure Information.For general queries on EMINENT please contact Dr Charlotte Summers (EMINENT Training Lead) via cs493@medschl.cam.ac.uk; and for informal queries regarding a particular post, please contact Prof Peter Openshaw at p.openshaw@imperial.ac.ukFor further information on EMINENT go to: https://www.ucl.ac.uk/eminent-consortium/Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.

Documents

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.